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What Are The Stages of Mesothelioma Cancer Development?

Mesothelioma Cancer

One rare form of cancer is called Mesothelioma, a malignant tumor in the mesothelial tissues of the lungs and the abdomen, arising from the inhalation of asbestos. Because it is rare many people are unaware of this fatal disease. There are many people who go undiagnosed and die of Mesothelioma.  While there is a growing awareness of asbestos hazards  to health, too many people have not learned about Mesothelioma and therefore do not understand its cause, nature, signs and treatment. Today,  physicians find it difficult to detect Mesothelioma as its symptoms are similar to other lung diseases such as pneumonia and lung cancer. Moreover, it can take many years, decades, for a person exposed to asbestos to develop Mesothelioma.

Mesothelioma Awareness

Being unaware of Mesothelioma poses higher risks since it deters diagnosis and treatment. A person undergoing treatment must know the different stages of the cancer or the extent of the disease. Chances of recovering from Mesothelioma and the kind of treatment depend on the stage of the illness.

Mesothelioma Staging Systems

There are basically two staging systems used for Pleural Mesothelioma (lungs): TNM system and Brighan system. These staging systems are also used in other kinds of cancers; however, the first is commonly used. There is no established method in determining the stage of the Peritoneal Mesothelioma cancer (abdominal) so the TNM system is used.

The Mesothelioma TNM System

There are three variables in the TNM system: tumor, lymph nodes and metastasis. In the earliest stage of Mesothelioma, stage 1 (one), the malignant Mesothelioma cells start to grow and multiply only one layer of the pleura. The pleura is the membrane that encloses the lungs and lines the wall of the chest cavity. However, there are some instances wherein the pericardium (membrane that covers the heart) and diaphragm cover are already affected. In this case, the cancer patient is still in stage 1 (one) Mesothelioma.

In the second stage, the two layers of the pleura are already affected by Mesothelioma. Take note, however, that in this stage, only one side of the body is affected. Normally, the pleura produces only small amount of lubricating fluid that allows easy expanding and contracting of the lungs. The excess fluid is absorbed by the blood and the lymph vessels so there’s a balance between the amount of fluid produced and removed. During the second stage Mesothelioma, fluid starts to build up between the membrane of the lungs and the membrane of the chest wall, resulting to pleural effusion. The increase in the volume of fluid produced causes shortness of breath and chest pain. Other Mesothelioma cancer patients experience dry and persistent cough. Diagnosis of the pleural effusion is achieved through a chest x-ray.

Stage 3 (three) Mesothelioma means that the malignant cells have already spread to the chest wall, esophagus and the lymph nodes on one part of the chest. The patient may suffer severe pain near the parts affected. When not treated immediately or when the Mesothelioma patient doesn’t respond well to medication, the cancer may advance to the fourth stage.

Stage 4 (four) Mesothelioma is formidable since at this stage the Mesothelioma cells have penetrated into the bloodstream and other organs in the body like the liver, the bones and the brain. The lymph nodes on the other side of the chest may also be affected by Mesothelioma in stage 4 (four).

The Mesotheloma Brighan System

Brighan staging system, on the other hand, determines whether the Mesothelioma can be surgically removed or not and whether the lymph nodes are affected or not.

Stage 1 (one) Mesothelioma, the lymph nodes are not yet affected and the patient can still recover through surgery.

Stage 2 (two) Mesothelioma, surgery can still be executed but some lymph nodes have already been infiltrated by the cancer cells.

Stage 3 (three) Mesothelioma, the heart and chest wall are already affected; thus, surgery is no longer advisable. The lymph nodes in this stage, however, may or may not be affected.

Stage 4 (four) Mesothelioma, the final stage, cancer cells have already gone to the bloodstream and other parts of the body like the heart, brain, bone and liver. In most cases, a patient who has reached stage 4 (four) Mesothelioma only has four to twenty-four months to live.

Mesothelioma: Causes and Treatments in Simple Terms

Mesothelioma is an uncommon form of cancer that affects the body of many retired factory, military, shipyard and construction workers. While there are many aggravating factors that can worsen the severity of a mesothelioma case, it has been demonstrated with strong evidence to be primarily caused by exposure to asbestos.

What is Mesothelioma?

Mesothelioma tumors affect the protective lining surrounding a great deal of the body’s internal organs. These tumors can lead to the development of severe chest pain, low blood sugar levels, fatigue, anemia, shortness of breath and even lung collapse. Mesothelioma tumors can spread all over the body, with the exception of the brain, skeletal system and adrenal glands. Mesothelioma symptoms can take a very long time to manifest, in some cases at least 15 years. The fact that some cases are not diagnosed until decades after the initial asbestos exposure that caused them makes the cancer very hard to treat or prevent.

How Does Asbestos Exposure Occur?

Asbestos is a general term for a wide range of minerals used throughout human history, and more recently in a variety of industrial settings. Its efficiency as a cheap insulator led to it becoming very popular in homes built before the 1970s, as well as military ships during World War II. In their raw mineral form, small asbestos particles can easily become airborne, where they pose a huge risk of being inhaled. Inside the body, these abrasive dust fragments lead to the development of cancers. Many shipyard workers and factory personnel were exposed to asbestos long before the correlation between asbestos and mesothelioma was commonly noted. Modern workers who renovate older buildings are also at risk for mesothelioma inducing asbestos exposure.

How to detect Mesothelioma and What to do About it?

Diagnosis of this desease is complicated by the similarity of mesothelioma symptoms to a many other common diseases. Generaly, a complete detailed review of a patient’s medical history as well as their occupational history and experience is necessary in obtaining an accurate diagnosis. The historic study is usually followed by thorough physical examinations including chest X-rays, lung function tests and CT scans or MRIs.

There are few treatments  for mesothelioma that can provide some sort of cure by themselves, and surgery has proven frequently ineffective on mesothelioma.   Chemotherapy is the most commonly administered effective therapy, and immunotherapy treatments have provided various results, some of which were in fact successful.  There are clinical trials of new treatments that are in Phase II and Phase III study that are proving to be very hopeful of a cure to mesothelioma cancer.

Get more information about Asbestos Exposure, here!

Get more information about Mesothelioma Causes and Treatments, here!

 

 

 

What kinds of tests for Mesothelioma can the doctor request?

Pleural Mesothelioma is easier to diagnose then Peritoneal Mesothelioma.

There are three (3) useful tests when beginning to diagnose your condition:

With the use of X-rays a photographic image is obtained from low doses of high energy radiation.  High doses of X-rays can be used to treat some cancers and is called radiation therapy.

Continue reading What kinds of tests for Mesothelioma can the doctor request?